Schedule
- Day 1: Sunday Oct. 6, 2024
- Day 2: Monday, Oct. 7, 2024
- Day 3: Tuesday, Oct. 8, 2024
- Day 4: Wednesday, Oct. 9, 2024
- Day 5: Thursday, Oct. 10, 2024
15:00-18:00 Participant arrival (check in hotel) and registration (*** location)
15:00-18:00 Must register to get badge to attend Reception
18:00-20:00 Reception “Vino español” Molinos del Río
20:00 Dinner- On your own (Most restaurants open at this time – a few may be open earlier)
08:00-08:30 Registration
08:30-09:00 Opening Ceremony
John Pierce Wise, Sr., ISTERH President, Univ. of Louisville, USA
Emma Martinez-Lopez, ISTERH-2024 Conference Co-President, Univ. of Murcia, Spain
Jamie Young, ISTERH-2024 Conference Co-President, Univ. of Louisville, USA
TBN, Leader of Univ. of Murcia
09:00-09:15 Group photo (All attendees)
Room A
9:15-10:00 Plenary Session 1
Presentation: Crossing Borders-Tracing elements: A Pan-African Study of Human Contamination Through Migrant Blood Samples
Speaker: Octavio Luzardo, University of Las Palmas de Gran Canaria Spain
10:00-10:15 Poster Flash Talks
10:15-10:45 Poster Session - Odd Numbers Attended (Courtyard) & Coffee Break (Courtyard)
Room A
10:45-11:45 Symposium 1: Ferroptosis: Crosstalk of Iron and Selenium Metabolism – from Mechanisms to Translational Finding
Chairs: Barbara R. Cardoso, Monash University, Australia, Lucia Seale, University of Hawaii at Manoa, USA
10:45-11:00 Title: Selenocysteine Recycling in Neuroblastoma a New Paradigm of Ferroptosis Inductio
Speaker: José Pedro Friedmann Angeli, University of Würzburg, Würzburg, Germany
11:00-11:05 Questions for Dr. Angeli
11:05-11:20 Title: Impact of the Loss of Selenocysteine Lyase and Selenium Deficiency on Ferroptosis in Primary Cardiomyocytes
Speaker: Briana Shimada, University of Hawaii at Manoa, Honolulu, USA
11:20-11:25 Questions for Dr. Shimada
11:25-11:40 Title: Elucidating the Role of Ferroptosis in Parkinson’s Diseas
Speaker: Laura Mahoney Sanchez, The Francis Crick Institute, London, UK
11:40-11:45 Questions for Dr. Mahoney Sanchez
Room B
10:45-11:45 Symposium 2: Environmental Biomonitoring for Trace Elements in Marine Organisms
Chairs: Emma Martínez-López, University of Murcia, Spain, Octavio P. Luzardo, University of Las Palmas de Gran Canaria, Spain
10:45-11:00 Title: Sentinel Bivalve and Fish Species for Pollution Monitoring and Ecosystem Health Disturbance Assessment for Trace Elements
Speaker: Urtzi Izagirre, University of the Basque Country, Spain
11:00-11:05 Questions for Dr. Izagirre
11:05-11:20 Title: Sharks as Monitors of Mercury in the Sea. Do they Exhibit Resistance to Mercury?
Speaker: Annalisa Zaccaroni, University of Bologna, Italy
11:20-11:25 Questions for Dr. Zaccaroni
11:25-11:40 Title: Effects of Widespread Metal Pollutants on Cetaceans: Focus on Oxidative Stress Biomarkers
Speaker: Emma Martinez-Lopez, University of Murcia, Spain
11:40-11:45 Questions for Dr. Martinez-Lopez
11:45-13:15 Lunch - provided onsite (Courtyard)
Room B
13:15-14:00 Plenary Session 2: One Environmental Health
Presentation: Metals and One Environmental Health
Speaker: John Pierce Wise, Sr. University of Louisville, USA
14:00-14:15 Poster Flash Talks
14:15-14:45 Poster Session - Even Numbers Attended (Courtyard) & Coffee Break (Courtyard)
Room A
14:45-16:45 Symposium 3: High-Throughput Technology and Health Effects
Chair: Jia Guang, Peking University, China
14:45-15:00 Title: Comparative Study of Effect of Different Heavy Metals on Developmental Neonatal Brain
Speaker: Hideko Sone, Yokohama University of Pharmacy, Japan
15:00-15:05 Questions for Dr. Sone
15:05-15:20 Title: Single-cell RNA-seq SHERRY Reveals Arsenic-Aquaporin 3-Induced Transcriptome Adaptation
Speaker: Jun Xia, Creighton University, USA
15:20-15:25 Questions for Dr. Xia
15:25-15:40 Title: Predictive Metabolomics Signatures for Safety Assessment of Metal Oxide Nanoparticles
Speaker: Xiang Wang, University of California, Los Angeles, USA
15:40-15:45 Questions for Dr. Wang
15:45-16:00 Title: Role of Copper-Related Proteome in Neurotoxicity of Rats following Lead Exposure
Speaker: Weixuan Wang: North china University of science and Technology, China
16:00-16:05 Questions for Dr. Wang
16:05-16:20 Title: Respiratory Toxicity Mechanism and Biomarkers of Chromates Based on Multiomics Analysis
Speaker: Guiping Hu, Beihang University, China
16:20-16:25 Questions for Dr. Hu
16:25-16:40 Title: Simultaneous Effects of Metal Content Homeostasis and Microbiota Composition in Manganese Exposed Mice
Speaker: Tian Chen: Capital Medical University, China
16:40-16:45 Questions for Dr. Chen
Room B
14:45-16:45 Symposium 4: Let’s Talk About Sex - Impacts on Metal-Associated Diseases
Chairs: Jamie Young Wise, University of Louisville, USA, John Wise Jr., University of Louisville, USA
14:45-15:00 Title: Environmental Elements and Cardiometabolic Disorders: Recent Observations in the Sex-Specific, Sex Steroids Pathways
Speaker: Simin Liu, Brown University, USA
15:00-15:05 Questions for Dr. Liu
15:05-15:20 Title: Arsenic Exposures and Sex-Specific Differences in Development of Atherosclerosis in Mice
Speaker: Koren Mann, McGill University, Canada
15:20-15:25 Questions for Dr. Mann
15:25-15:40 Title: Arsenic-Induced Malignant Giant Cell Phenotype in Human Ovarian Epithelia is Mediated by NF-kB Inflammatory Pathway
Speaker: Diana Azzam, Florida International University, USA
15:40-15:45 Questions for Dr. Azzam
15:45-16:00 Title: Sex Differences in Metal Exposures and Type 2 Diabetes (T2D) Risk
Speaker: Tongzhang Zheng, Brown University, USA
16:00-16:05 Questions for Dr. Zheng
16:05-16:20 Title: Exposure to Hexavalent Chromium Results in Sexually Dimorphic Hepatic Outcomes
Speaker: Jamie Young Wise, University of Louisville, USA
16:20-16:25 Questions for Dr. Young Wise
16:25-16:40 Title: The Impact of Sex Differences in the Role of Magnesium in Liver Disease Prevention and Management
Speaker: Xuehong Zhang, Harvard University Medical School, USA
16:40-16:45 Questions for Dr. Zhang
17:30-19:30 Culture Program-1: Murcia Panoramic Walking Tour
20:00 Dinner- On your own (Most restaurants open at this time – a few may be open earlier)
08:00-08:30 Registration
Room A
8:30-9:50 Symposium 5: Epidemiology, Mechanisms, and Genetics of Manganese Homeostasis and Neurotoxicity
Chairs: Somshuvra Mukhopadhyay, University of Texas, USA, Tomas Guilarte, Florida International University, USA
8:30-8:45 Title: Role of SLC30A10 in Modulating Mn Homeostasis and Neurotoxicity
Speaker: Somshuvra Mukhopadhyay, University of Texas at Austin, USA
8:45-8:50 Questions for Dr. Mukhopadhyay
8:50-9:05 Title: Inherited Manganese Transporter Defects – from Fish Tank to Bedside
Speaker: Karin Tuschl, UCL GOS Institute of Child Health, London, UK
9:05-9:10 Questions for Dr. Tuschl
9:10-9:25 Title: Child Environmental Manganese Exposure and Developmental Effects – the Role of Transporter Genetics
Speaker: Karin Broberg, Lund University/Karolinska Institut, Sweden
9:25-9:30 Questions for Dr. Broberg
9:30-9:45 Title: Pathophysiological Changes in the Cerebellum and Brainstem in the Slc39a14-Knockout Mouse Model of Childhood-Onset Manganese-Induced Dystonia-Parkinsonism
Speaker: Tomas Guilarte, Florida International University, USA
9:45-9:50 Questions for Dr. Guilarte
Room B
8:30-9:50 Symposium 6: Forging Metal Toxicology Experts: An All-Trainee Session
Chairs: Idoia Meaza, University of Louisville, USA,
Co-chair: Aggie Williams, University of Louisville, USA
8:30-8:45 Title: Effects of Particulate Hexavalent Chromium on the Somatic Genomic Landscape
Speaker: Idoia Meaza, University of Louisville
8:45-8:50 Questions for Ms. Meaza
8:50-9:05 Title: Hexavalent Chromium Impacts of the BCDX2 Repair Complex in Human and Alligator Lung Cells
Speaker: Aggie Williams, University of Louisville, USA
9:05-9:10 Questions for Ms. Williams
9:10-9:25 Title: Risk of low-dose metal mixture-induced cardiometabolic diseases in the ApoE mouse model
Speaker: Nivetha Kamalavannan Subramaniam
9:25-9:30 Questions for Ms. Kamalavannan
9:30-9:45 Title: Sexual Dimorphism in Cumulative Metal Measurements in Bone and Teeth
Speaker: Thomas Grier, Purdue University, USA
9:45-9:50 Questions for Dr. Grier
09:50-10:20 Poster Viewing -Unattended (Courtyard) & Coffee Break (Courtyard)
Room A
10:20-12:00 Symposium 7: Manganese in Neurodegenerative Parkinsonia Disorders: Mechanisms, Diagnosis and Treatment
Chairs: Wei Zheng, Purdue University, USA, Xiaoli Shen, Qingdao University, China
10:20-10:35 Title: Genetic and Metabolic Pathways altered by Chronic Low-Level Excess Manganese
Speaker: Aaron B. Bowman, Purdue University, USA
10:35-10:40 Questions for Dr. Bowman
10:40-10:55 Title: Association between Altered Adult Neurogenesis in SVZ and Manganese-induced Non-motor Syndromes in Manganism
Speaker: Wei Zheng, Purdue University, USA
10:55-11:00 Questions for Dr. Zheng
11:00-11:15 Title: Bone Manganese, a Measure of Cumulative Exposure, and Associations with Neurological Function in Manganese-Exposed Workers
Speaker: Ellen M. Wells, Purdue University, USA
11:15-11:20 Questions for Dr. Wells
11:20-11:35 Title: Using Magnetic Resonance Imaging to Assess the Impact of Environmental Manganese on the Developing Brain in an Appalachian Cohort of Children
Speaker: D. Alex Edmondson, University of Cincinnati, USA
11:35-11:40 Questions for Dr. Edmondson
11:40-11:55 Title: Vitamin E Protects Dopaminergic Neurons against Manganese-induced Neurotoxicity through Stimulation of CHRM1 and KCNJ4
Speaker: Xiaoli Shen, Qingdao University, China
11:55-12:00 Questions for Dr. Shen
Room B
10:20-12:00 Symposium 8: Trace Elements as Contaminants in Aquatic Environments
Chairs: Luisa M. Vera, University of Murcia, Spain, Gabriel López Berenguer, University of Murcia, Spain
10:20-10:35 Title: Ecotoxicity and Risk Assessment of Environmentally Available Trace Elements
Speaker: Miriam Hampel, University of Cádiz, Spain
10:35-10:40 Questions for Dr. Hampel
10:40-10:55 Title: An Overview of the Potential Toxicity of Environmental and Supra-Environmental Levels of Metallic Nanoparticles in Marine Organisms
Speaker: Cláudia Mieiro, University of Aveiro, Portugal
10:55-11:00 Questions for Dr. Mieiro
11:00-11:15 Title: Could Trace Elements Currently Neglected by Environmental Policies be Deemed as Emerging Contaminants in Marine Ecosystems?
Speaker: Ionan Marigómez, University of the Basque Country, Spain
11:15-11:20 Questions for Dr. Marigómez
11:20-11:35 Title: Challenges and Impacts in Mixing Pollutants in Mediterranean Sea: Exploring Immunological and Ecotoxicological Implications
Speaker: Cristóbal Espinosa Ruiz, University of Murcia, Spain
11:35-11:40 Questions for Dr. Espinosa
11:40-11:55 Title: The Effect of Heavy Metals on Fish is Time-Of-Day Dependent: Toxicity Rhythms
Speaker: Luisa M. Vera, University of Murcia, Spain
11:55-12:00 Questions for Dr. Vera
12:00-13:30 Lunch- provided onsite (Courtyard)
ISTERH Council Lunch Meeting (located in ***)
Room B
13:30-14:30 Special Session 1: Resources, Grants, and Career Development
Chairs: Fred Tyson, National Institute of Environmental Health, USA, Leroy Worth, Jr., National Institute of Environmental Health, USA
13:30-13:45 Title: Precision environmental health, exposomics and NIEHS priorities
Speaker: Frederick (Fred) L. Tyson, National Institute for Environmental Health Sciences (NIEHS), USA
13:45-13:50 Questions for Dr. Tyson
13:50-14:05 Title: NIH PEER REVIEW: A New Era “The more things change The more they stay the same!”
Speaker: Leroy Worth Jr., National Institute for Environmental Health Sciences (NIEHS), USA
14:05-14:10 Questions for Dr. Worth
14:10-14:25 Title: ***TBD
Speaker: Konstantin Salnikow, National Cancer Institute (NCI), USA
14:25-14:30 Questions for Dr. Salnikow
15:15-15:25 Board bus for departure to Cultural Program
16:00-19:30 Culture Program-2 Visit to Cartagena (Roman Theatre Museum, Molinete Roman Forum Museum, etc)
19:30-20:30 Dinner- On your own in Cartagena
22:00-22:20 Board bus for departure to Cultural Program
23:00 Arrive back in Murcia
08:00-08:30 Registration
Room A
8:30-10:30 Symposium 9 (Room A): Environmental Toxicants in The Pathogenesis of Alzheimer's and Related Neurodegenerative Disorders
Chair: Yansheng Du, Indiana University, USA
8:30-8:45 Title: Gene XZ Environment Interaction of the SORL1 Genetic Variant of Alzheimer’s Disease Coupled to an Embryonic Lead Exposure in a Zebrafish CRISPR Mutant
Speaker: Jennifer L. Freeman, Purdue University, USA
8:45-8:50 Questions for Dr. Freeman
8:50-9:05 Title: Exposure to Fine and Ultrafine Particulate Matter Accelerates Memory Impairment and AD-Like Neuropathology in APP-KI Mice
Speaker: Masashi Kitazawa, University of California, Irvine, USA
9:05-9:10 Questions for Dr. Kitazawa
9:10-9:25 Title: Identifying Imaging Biomarkers for Manganese Toxicity in Occupationally Exposed Welders
Speaker: Chongli Yuan, Purdue University, USA
9:25-9:30 Questions for Dr. Yuan
9:30-9:45 Title: Hif-1α/Tfrc-Mediated Mitochondria-Associated Ferroptosis of Astrocyte Exerts a Crucial Role in Depressive- and Anxiety-Like Behavior Following Lead Exposure
Speaker: Yansh Zhang, North China University of Science and Technology, China
9:45-9:50 Questions for Dr. Zhang
9:50-10:05 Title: Neuroimaging and Metabolomics Approach for Lipid Constituents of Myelin and Positive Iron MRI Contrast in AD
Speaker: Uzay Emir, Purdue University, USA
10:05-10:10 Questions for Dr. Emir
10:10-10:25 Title: Role of PAI-1 in Pb-Induced Amyloid Pathology
Speaker: Yansheng Du, Indiana University, USA
10:25-10:30 Questions for Dr. Du
Room B
8:30-10:30 Symposium 10 (Room B): Mechanisms of Metal Carcinogenesis
Chairs: Zhishan Wang, Stony Brook University, USA, James T.F. Wise, Louisiana State University, USA
8:30-8:45 Title: Abnormal Signaling in Arsenic-Induced Bladder Carcinogenesis
Speaker: Chendil Damodaran, Texas AM University, USA
8:45-8:50 Questions for Dr. Damodaran
8:50-9:05 Title: Epitranscriptomic Mechanism of Arsenic and Benzo(a)pyrene Co-Exposure-Induced Cell Transformation and Tumorigenesis
Speaker: Zhishan Wang, Stony Brook University, USA
9:05-9:10 Questions for Dr. Wang
9:10-9:25 Title: Hexavalent Chromium-Induced Metabolic Changes in Human Lung Cells
Speaker: James T.F. Wise, Louisiana State University Agriculture Center, Baton Rouge, USA
9:25-9:30 Questions for Dr. Wise
9:30-9:45 Title: Chronic Hexavalent Chromium Exposure Activates Non-Canonical NFκB Pathway to Promote Immune Check Point Molecule PD-L1 Expression
Speaker: Chengfeng Yang, Stony Brook University, USA
9:45-9:50 Questions for Dr. Yang
9:50-10:05 Title: The Role of Histone Acetyltransferase MOF in Cr(VI)-Induced Lung Carcinogenesis
Speaker: Hong Sun, New York University, USA
10:05-10:10 Questions for Dr. Sun
10:10-10:25 Title: circSATB2, a Novel Regulator of Arsenic-Induced Carcinogenesis
Speaker: Yvonne Fondufe-Mittendorf, Van Andel Institute, USA
10:25-10:30 Questions for Dr. Fondufe-Mittendorf
10:30-11:00 Poster Session - Odd Numbers Attended (Courtyard) & Coffee Break (Courtyard)
Room A
11:00-12:00 Symposium 11 (Room A): Zinc in the Context of Human Health Outcomes: How Much Is Needed and How Much Is too Much?
Chairs: Malek El Muayed, Northwestern University, USA, Lu Cai, University of Louisville, USA
11:00-11:15 Title: Zinc Isotopes, Oxidative Stress, and Cardiometabolic Health in Adult Populations
Speaker: Irene Martinez-Morata, Columbia Mailman School of Public Health, USA
11:15-11:20 Questions for Dr. Martinez-Morata
11:20-11:35 Title: How Much is Too Much: Does Excess Zinc Increase the Risk for Type 2 Diabetes Through Zinc Overload and Toxicity in Insulin Producing Pancreatic Islets in Susceptible Individuals?
Speaker: Malek El Muayed, Northwestern University, USA
11:35-11:40 Questions for Dr. El Muayed
11:40-11:55 Title: Portable X-Ray Fluorescence for the Assessment of Zinc in Nail Clippings
Speaker: David Fleming, Mount Allison University, Canada
11:55-12:00 Questions for Dr. Fleming
Room B
11:00-12:00 Symposium 12 (Room B): Molecular Interactions Between Essential Trace Elements and Toxic Metal Ions
Chair: Andrea Hartwig, Karlsruhe Institute of Technology, Germany
11:00-11:15 Title: Selective Interaction of Arsenic with Zinc Containing Proteins
Speaker: Ke Jian Liu, Stony Brook University, USA
11:15-11:20 Questions for Dr. Liu
11:20-11:35 Title: Silver Toxicity Towards Zinc Fingers and Related Structures, and Protective Role of GSH
Speaker: Wojciech Bal, Polish Academy of Sciences, Poland
11:35-11:40 Questions for Dr.Bal
11:40-11:55 Title: Zinc Binding Structures as Sensitive Targets for Toxic Metal Compounds
Speaker: Andrea Hartwig, Karlsruhe Institute of Technology, Germany
11:55-12:00 Questions for Dr. Hartwig
12:00-13:30 Lunch- provided onsite (Courtyard)
ISTERH Council Lunch Meeting (located in ***)
Room A
13:00-15:00 Symposium 13 (Room A): Identifying Effective Biomarkers of Metal Exposures with Direct Relevance for Neurological Function
Chair: Aaron Specht, Purdue University, USA
13:00-13:15 Title: An Examination of Early Life Zinc Levels and Late Adulthood Cognitive Function: Results from the St. Louis Baby Tooth Study
Speaker: Marc Weisskopf, Harvard T.H. Chan School of Public Health, USA
13:15-13:20 Questions for Dr. Weisskopf
13:20-13:35 Title: Firearm-Related Lead Exposure and Child Lead Levels in the United States, 2012-2018
Speaker: Christian Hoover, Brown University, USA
13:35-13:40 Questions for Dr. Xia
13:40-13:55 Title: Sexual Dimorphism in Cumulative Metal Measurements in Bone and Teeth
Speaker: Thomas Grier, Purdue University, USA
13:55-14:00 Questions for Mr. Wang
14:00-14:15 Title: Synchrotron X-Ray Analysis of Nanoscale Metal Distributions in Human Olfactory Bulb
Speaker: Jake Brooks, University of Warwick, UK
14:15-14:20 Questions for Dr. Brooks
14:20-14:35 Title: Cerebrospinal Fluid Metals and Metabolomics Profiles in ALS Pathogenesis
Speaker: Per M Roos, Kolinkska Institutet, Sweden
14:35-14:40 Questions for Dr. Roos
14:40-14:55 Title: Air Pollutant Exposures and Biomarkers of Metal Exposures
Speaker: Jae Hong Park, Purdue University, USA
14:55-15:00 Questions for Dr. Park
Room B
13:00-15:00 Symposium 14 (Room B): Molecular Mechanisms of Arsenic Toxicity
Chair: Yinsheng Wang, University of California Riverside, USA
13:00-13:15 Title: Mutational signatures analysis reveals zinc resolves select ultraviolet radiation-induced mutations enhanced by arsenic co-exposure
Speaker: Rachel M. Speer, University of New Mexico, USA
13:15-13:20 Questions for Dr. Speer
13:20-13:35 Title: The “Dark Side” of NRF2: Implications in Arsenic-Induced Carcinogenicity and Diabetogenicity
Speaker: Donna Zhang, Scripps Florida, USA
13:35-13:40 Questions for Dr. Zhang
13:40-13:55 Title: RING Finger E3 Ubiquitin Ligases as Targets of Arsenic Toxicity
Speaker: Yinsheng Wang: University of California Riverside, USA
13:55-14:00 Questions for Dr. Wang
14:00-14:15 Title: Arsenic-Induced Carcinogenesis Requires Nrf2-Dependent Biosynthesis of Oncometabolites Cholesterol and Methylmalonate
Speaker: Fei Chen, Stony Brook University, New York
14:15-14:20 Questions for Dr. Chen
14:20-14:35 Title: The Role of Gut Microbiome in Arsenic Toxicity
Speaker: Kun Lu, University of North Carolina at Chapel Hill, USA
14:35-14:40 Questions for Dr. Lu
14:40-14:55 Title: Overexpression of transthyretin and β-trace in the Xenopus laevis choroid plexus ameliorates the effects of lead poisoning on thyroid hormone mediated changes in brain development
Speaker: Christopher K Thompson, Assistant Professor, School of Neuroscience, Virginia Tech
14:55-15:00 Questions for Dr. Thompson
15:00-15:30 Poster Session - Even Numbers Attended (Courtyard) & Coffee Break (Courtyard)
Room A
15:30-16:30 Symposium 15 (Room A): Current Status and Future Directions of Zinc and Iron Requirements
Chair: Jeanne Freeland-Graves, University of Texas, USA
15:30-15:45 Title: Global Trends and Future Directions in Estimation and Prediction of Zinc and Iron Status
Speaker: Jeanne Freeland-Graves and Mercy Sosanya, University of Texas at Austin, USA
15:45-15:50 Questions for Dr. Freeland-Graves
15:50-16:05 Title: Determination of Zinc Intake and Status in Mothers and Infants
Speaker: Louise Brough, Massey University, New Zealand
16:05-16:10 Questions for Dr. Brough
16:10-16:25 Title: A Mathematical Model Incorporating Absorption Rate as a Distribution Variable to Estimate Iron Requirements
Speaker: Katsuhiko Yokoi, Seitoku University, Japan
16:25-16:30 Questions for Dr. Yokoi
Room B
15:30-16:30 Symposium 16 (Room B): Let’s Talk About Sex across the Lifespan in Metal-Associated Disease
Chairs: Jamie Young, University of Louisville, USA, John Wise Jr., University of Louisville, USA
15:30-15:45 Title: Sexual epigenetic dimorphism in the placenta and toxicant susceptibility
Speaker: Rebecca Fry, University of North Carolina, USA
15:45-15:50 Questions for Dr. Fry
15:50-16:05 Title: A Toxic Aging Coin Approach Provides Key Insights on Age Differences and Aging Effects of Hexavalent Chromium Neurotoxicity
Speaker: Name: John Wise Jr., University of Louisville, USA
16:05-16:10 Questions for Dr. Wise, Jr.
16:10-16:25 Title: Transgenerational Impact of Mercury Exposure in Male and Female Zebrafish
Speaker: Michael J Carvan, University of Wisconsin Milwaukee, USA
16:25-16:30 Questions for Dr. Carvan
16:30-16:45 Break (no coffee)
Room A
16:45-17:45 Symposium 17 (Room A): Association of Trace Elements with Gut Microbiota
Chairs: Carmen Martínez Graciá, University of Murcia, Spain, Nieves Ortega Hernández, University of Murcia, Spain
16:45-17:00 Title: Modulation of Gut Microbiota through Trace Elements Intake
Speaker: Carmen Martínez Graciá, University of Murcia, Spain
17:00-17:05 Questions for Dr. Martínez Graciá
17:05-17:20 Title: Factors Influencing Bioavailability of Trace Elements Focusing on Gut Microorganism
Speaker: Marina Santaella Pascual, University of Murcia, Spain
17:20-17:25 Questions for Dr. Santaella
17:25-17:40 Title: Mineral Intake and Mineral Status During Pregnancy and Lactation, and the Role on Offspring Microbiota
Speaker: Clara Suárez Martínez, University of Murcia, Spain
17:40-17:45 Questions for Dr. Suárez
Room B
16:45-17:45 Symposium 18 (Room B): Human Health and the Exposome – an Example of Cadmium Effects in Different Organs and Exposures
Chair: Lu Cai, University of Louisville, USA
16:45-17:00 Title: Cd Toxicity in Various Tissues Including the Kidney and PPARδ-Mediated Pathways
Speaker: Jinyong Lee, Aichi Gakuin University School of Pharmacy, Japan
17:00-17:05 Questions for Dr. Lee
17:05-17:20 Title: Inhibition of DNA Repair Complexes by Cadmium
Speaker: Aishwarya Prakash, University of South Alabama, USA
17:20-17:25 Questions for Dr. Prakash
17:25-17:40 Title: Prenatal Exposure to Cd Increased High Risk of Multi-Organ’s Pathogenesis in Response to High-Fat Diet
Speaker: Lu Cai, University of Louisville, USA
17:40-17:45 Questions for Dr. Cai
19:30-19:50 Board the Bus for Gala Banquet
20:15 Wine Tasting, Awards Presentation, Gala Banquet (“Palacete de la Seda” + performance), Explore Palace & Enjoy Music
00:00 Board bus to return
08:00-08:30 Registration
Room A
10:00-11:20 Symposium 19: Role of a Benchtop Total Reflection X-Ray Fluorescence (TXRF) Spectroscopy for Trace and Multi-Elemental Analysis of Human Tissues
Chair: Ana Pejović-Milić, Toronto Metropolitan University, Canada
10:00-10:15 Title: Total X-ray Fluorescence Spectroscopy as a Reliable Analytical Technique for Use in Clinical Laboratories for Multi-Element Analysis of Biological Fluids
Speaker: Jasna Jablan, University of Zagreb Faculty of Pharmacy and Biochemistry, Croatia
10:15-10:20 Questions for Dr. Jablan
10:20-10:35 Title: Elemental Analysis of Animal Tissues with the Total Reflection X-ray Fluorescence - Examples of Study, their Advantages and Limitations
Speaker: Joanna Chwiej, University of Krakow, Poland
10:35-10:40 Questions for Dr. Chwiej
10:40-10:55 Title: Role of Total Reflection X-ray Spectrometry in Nanomedicine and Trace Element Analysis
Speaker: Ana Pejović-Milić, Toronto Metropolitan University, Canada
10:55-11:00 Questions for Dr. Pejović-Milić
11:00-11:15 Title: Analytical Possibilities of Total Reflection Spectrometry in the Field of Food and Nutrition
Speaker: Eva Marguí, University of Girona, Spain
11:15-11:20 Questions for Dr.Margui
Room B
Room A
11:20-12:20 Special Session 2: Emerging Topics in Medical Applications in Trace Element Research
Chair: David Fleming, Mount Allison University, Canada
11:20-11:35 Title: Selected from Submitted Abstracts
Speaker: Selected from Submitted Abstracts
11:35-11:40 Questions for Speaker
11:40-11:55 Title: Selected from Submitted Abstracts
Speaker: Selected from Submitted Abstracts
11:55-12:00 Questions for Speaker
12:00-12:15 Title: Selected from Submitted Abstracts
Speaker: Selected from Submitted Abstracts
12:15-12:20 Questions for Speaker
Room B
11:20-12:20 Special Session 3: Emerging Topics in One Environmental Health in Trace Element Research
Chair: John Pierce Wise, Sr., University of Louisville, USA
11:20-11:35 Title: Selected from Submitted Abstracts
Speaker: Selected from Submitted Abstracts
11:35-11:40 Questions for Speaker
11:40-11:55 Title: Selected from Submitted Abstracts
Speaker: Selected from Submitted Abstracts
11:55-12:00 Questions for Speaker
12:00-12:15 Title: Selected from Submitted Abstracts
Speaker: Selected from Submitted Abstracts
12:15-12:20 Questions for Speaker
12:20-14:00 Lunch- provided onsite (Courtyard)
ISTERH Council Lunch Meeting (located in ***)
Room A
14:00-15:40 Symposium 21: M&M’s Detrimental Effects in Human Brains – Manganese and Mercury
Chairs: Linda Nie, Purdue University, USA, Xuemei Huang, Penn State University, USA
14:00-14:15 Title: The Complex Interplay between Neuroinflammation and the Dopaminergic and Cholinergic Brain Pathways in Mn-exposed Workers
Speaker: Brad Racette, Barrow Neurological Institute, USA
14:15-14:20 Questions for Dr. Racette
14:20-14:35 Title: Mechanisms of Manganese-induced Neuroinflammation and its Relevance to Biomarker Discovery
Speaker: Anumantha Kanthasamy, University of Georgia, USA
14:35-14:40 Questions for Dr. Kanthasamy
14:40-14:55 Title: In-Utero Mercury Exposure Effects on Childhood Developmental Delay in an Artisanal and Small Scale Gold Mining (ASGM) Region of the Peruvian Amazon, the CONAMAD Study
Speaker: William Pan, Duke University, USA
14:55-15:00 Questions for Dr. Pan
15:00-15:15 Title: Welding Fume and Related Metal Exposures are Associated with Features Resembling Alzheimer Disease At-Risk Populations
Speaker: Xuemei Huang, Penn State University, USA
15:15-15:20 Questions for Dr. Huang
15:20-15:35 Title: Mercury (Hg) and Selenium in Human Brain Tissue Using Synchrotron Micro-X-ray Fluorescence (µ-XRF)
Speaker: Linda Nie, Professor, Purdue University, USA
15:35-15:40 Questions for Dr. Nie
Room B
14:00-15:40 Symposium 22: Environmental Biomonitoring for Trace Elements in Humans
Chairs: Emma Martínez-López, University of Murcia, Spain, Octavio P. Luzardo, University of Las Palmas de Gran Canaria, Spain
14:00-14:15 Title: Human Biomonitoring of Biological Samples to Assess Metals and Metalloids Exposure in Mother-Child Pairs from Seville (Spain)
Speaker:. María Gracia Hinojosa Hidalgo, Universidad de Sevilla, Spain
14:15-14:20 Questions for Dr. Hinojosa
14:20-14:35 Title: Understanding the Potential Human Health Risks of Silver Nanoparticles: A Comprehensive Analysis of Intestinal Pro-Inflammatory Pathways from In Vitro and In Vivo Studies
Speaker: Marisa Freitas, University of Porto, Portugal
14:35-14:40 Questions for Dr. Freitas
14:40-14:55 Title: Biomonitoring of Inorganic Contaminants in a Population Cohort from La Palma Island Exposed to the Tajogaite Volcano Eruption (2021) and Its Relationship with Health Parameters
Speaker: Katherine Simbaña-Rivera, Universidad Católica del Ecuador, Ecuador
14:55-15:00 Questions for Dr. Simbaña-Rivera
15:00-15:15 Title: Influence of Smoking in the Body Burden of Chemical Elements: Role of Smoking Paper, Tobacco Origin and Electronic Cigarrettes
Speaker: Luis Alberto Henriquez-Hernández, Universidad de Las Palmas de Gran Canaria, Spain
15:15-15:20 Questions for Dr. Henriquez-Hernández
15:20-15:35 Title: Integration of Lead Exposure Assessment into Clinical Practice: Experience in the Cartagena Mining Area
Speaker: Juan Antonio Ortega-García, Clinical University Hospital Virgen de la Arrixaca, Murcia, Spain
15:35-15:40 Questions for Dr. Ortega-García
15:40-16:00 Closing Ceremony