Recent papers on Enzyme Kinetics published in scientific journals (from 1995).
Influence of product instability on the Michaelis-Menten kinetics under steady-state and rapid equilibrium assumptions.
The International Journal of Biochemistry, 27, 475-479, 1995.
Computer program for the equations describing the steady-state of enzyme reactions.
Cabios (Computer Applications in the Biosciences) 13, 159-167, 1997.
An alternative analysis of enzyme systems based on the whole reaction time evaluation of the kinetic parameters and initial enzyme concentration.
Journal Mathematical Chemistry, 42, 789-813, 2007.
Expression for the fractional modification in different monocyclic enzyme cascade systems: analysis of their validity tested by numerical integration.
The Bulletin of Mathematical Biology, 242, 743-754, 2006.
Kinetic analysis of the steady-state and transient phase of multicyclic cascades.
Acta Biochimica Polonica, 52, 765-780, 2005. Polonia
Mean residence times in linear compartmental system. Symbolic formulae for their direct Evaluation.
Bulletin of Mathematical Biology, 65, 279-308, 2003.
General linear compartment model with zero input: I. Kinetic equations.
BioSystems, 36, 121-133, 1995.
General linear compartment model with zero input: III. First passage residence time of enzyme systems.
BioSystems, 36, 145-156, 1995.
A method based on statistical moments to evaluate the kinetic parameters involved in unstable enzyme system.
Journal of Matematical Chemistry, 44, 379-404, 2008.
Mean lifetime and first-passage time of the enzyme species involved in an enzyme reaction. Application to unstable enzyme systems.
Bulletin of Mathematical Biology, 70, 1425-1449, 2007.
Analysis of progress curves of enzymatic reactions with unstable species.
Int. J. Biochem. Cell Biol. 28, 1371-1379, 1997.
García-Meseguer, M.J.; Vidal, J.A.; García-Cánovas, F.; Havsteen, B.H.; García-Moreno, M. y Varón, R.
Time course equations of the amount of substance in a linear compartmental system and their computerized derivation.
Biosystems, 59, 197-220, 2001.
Use of a windows program for simulation of the progress curves of reactants and intermediates involved in enzyme-catalyzed reactions.
BioSystems 54, 151-164, 2000.
Transient phase of enzyme reactions. Time course equations of the strict and the rapid equilibrium conditions and their computerized derivation.
BioSystems 50, 99-126, 1999.
Kinetic analysis of a general model of activation of aspartic proteinase zymogens.
Journal of Theoretical Biology, 39, 238-252, 2007.
Garrido del Solo, C.; Yago, J.M.; García-Moreno,M.; Havsteen, B.H.; Garcia-Cánovas, F.y Varón,R.
The kinetic effect of the inactivation of the enzyme-substrate complex in an enzymatic reaction with slow-binding inhibition.
Applied Mathematics and Comparation, 171, 450-463, 2005. Reino Unido
The influence of product instability on the slow-binding inhibition.
J. Enzyme Inhib. Med. Chem. 20 (4), 309-316, 2005. Reino Unido.
Time behaviour of modifier involved in the general mechanism of Boots and Morales assuming rapid equilibrium in the modifier bindings.
Journal of Mathematical Chemistry, 38, 1, 67-88, 2005. USA
Kinetic analysis of enzyme reactions with slow-binding inhibition.
BioSystems 51, 169-180, 1999.
Varón, R.; García-Cánovas, F; García-Moreno, M.; Valero, E.; Molina-Alarcón, M.; García-Meseguer, M.J.; Vidal de Labra, J.A. y Garrido-Del Solo, C.
Kinetic analysis of the general modifier mechanism of Botts and Morales involving a suicide substrate.
Journal of Theoretical Biology, 218, 355-374, 2002.
Moruno, M.A.; Garrido, C.; García-Moreno, M.; García-Cánovas, F. y Varón, R.
Kinetic analysis of enzyme systems with suicide substrate in the presence of a reversible, uncompetitive inhibitor.
Biosystems, 61, 5-14, 2001.
Moruno, M.A.; Garrido, C.; García-Moreno, M.; Havsteen, B.H.; García-Sevilla, F.; García-Cánovas, F. y Varón, R.
Kinetic analysis of enzyme systems with suicide substrate in the presence of a reversible competitive inhibitor, tested by simulated progress curves.
The International Journal of Biochemistry and Cell Biology, 33, 181-191, 2001.